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Mississippi River

Explore America's historic treasures on a cruise of the Mississippi River, a 2,320-mile waterway that flows through 10 states, from Minnesota to the Gulf of Mexico. Sailings on the Mississippi visit Civil War battlefields, restored plantations, rolling farmland and picturesque riverfront towns filled with Victorian-era architecture. 

Mississippi River cruises are easy to budget, as the upfront price covers accommodations, delectable meals, wine and beer with dinner, onboard entertainment and enriching lectures. A tour of local attractions at each port is also included.

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Limited-Time Offers: Mississippi River
Offers are subject to change or withdrawal at any time. Some discounts are not combinable with other promotions.
  • Save up to $3,000 per couple off 2021 cruises with American Queen Steamboat Company, plus receive $140 per couple in free onboard credit. Expires September 30. Click here.
  • Save up to $2,000 per couple off select American Cruise Lines sailings. Click here.
  • Fly for free from select gateways, plus save up to $1,000 per couple off select Viking cruises in certain cabin categories. Expires September 30. Click here.
  • Save $400 per couple off American Cruise Lines departures when you book nine months in advance. Click here.
  • Receive free shore excursions on select American Cruise Lines river cruises. Click here.
  • Enjoy a free open-bar cocktail hour every evening before dinner with American Cruise Lines. Click here.
  • Receive one free hotel night before your cruise with American Cruise Lines, plus transfers to your ship on the day of departure when you book one month in advance. Click here.

Mississippi River (To view the full itinerary, dates and prices, click "See prices.")
Vacation name Days Begins in Ends in Company Quality From
Highlights of the Mississippi River 5 New Orleans,
LA
New Orleans,
LA
ACL Deluxe See prices
Lower Mississippi River Cruise (Memphis to New Orleans) 8 Memphis,TN New Orleans,
LA
ACL Deluxe See prices
Mississippi River Cruise (New Orleans Roundtrip) 8 New Orleans,
LA
New Orleans,
LA
ACL Deluxe See prices
New Orleans & Southern Charms 2023 8 New Orleans,
LA
New Orleans,
LA
Viking Deluxe See prices
Heart of the Delta 2023 8 Memphis,TN New Orleans,
LA
Viking Deluxe See prices
Heart of the Delta 2023 8 New Orleans,
LA
Memphis,TN Viking Deluxe See prices
Southern Celebration 2023 8 New Orleans,
LA
New Orleans,
LA
Viking Deluxe See prices
Upper Mississippi River Cruise (St. Paul to St. Louis) 8 St. Paul,
MN
St. Louis,
MO
ACL Deluxe See prices
Upper Mississippi River Cruise (St. Louis to St. Paul) 8 St. Louis,
MO
St. Paul,
MN
ACL Deluxe See prices
Music Cities Cruise 2021 (Nashville to Memphis) 8 Nashville,
TN
Memphis,TN ACL Deluxe See prices
Music Cities Cruise 2021 (Memphis to Nashville) 8 Memphis,TN Nashville,
TN
ACL Deluxe See prices
New Orleans & Southern Charms 2022 8 New Orleans,
LA
New Orleans,
LA
Viking Deluxe See prices
Southern Celebration 2022 8 New Orleans,
LA
New Orleans,
LA
Viking Deluxe See prices
Lower Mississippi River Cruise (New Orleans to Memphis) 8 New Orleans,
LA
Memphis,TN ACL Deluxe See prices
Heart of the Delta 2022 8 Memphis,TN New Orleans,
LA
Viking Deluxe See prices
America's Heartland 2023 (St. Paul to St. Louis) 8 St. Paul,
MN
St. Louis,
MO
Viking Deluxe See prices
America's Heartland 2023 (St. Louis to St. Paul) 8 St. Louis,
MO
St. Paul,
MN
Viking Deluxe See prices
Heart of the Delta 2022 8 New Orleans,
LA
Memphis,TN Viking Deluxe See prices
America's Heartland 2022 (St. Paul to St. Louis) 8 St. Paul,
MN
St. Louis,
MO
Viking Deluxe See prices
America's Heartland 2022 (St. Louis to St. Paul) 8 St. Louis,
MO
St. Paul,
MN
Viking Deluxe See prices
The Evolution of Rock 'n' Roll 2021 (New Orleans to Memphis) 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
Cajun Creole Culinary Experience 2021 (New Orleans to Memphis) 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
The Evolution of Rock 'n' Roll 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Big Band 2021 (New Orleans Roundtrip) 9 New Orleans,
LA
New Orleans,
LA
Steamboat Deluxe See prices
Charms of the South 2021 (New Orleans to Memphis) 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
American Culinary Experience 2021 (Alton to Cincinnati) 9 St. Louis,
MO
Cincinnati,
OH
Steamboat Deluxe See prices
Heart of the Mississippi 2021 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Home for the Holidays 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Southern Sampler 2021 9 New Orleans,
LA
New Orleans,
LA
Steamboat Deluxe See prices
Charms of the South 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Community Outreach 2021 9 Louisville,
KY
Alton,
IL
Steamboat Deluxe See prices
American Culinary Experience 2021 (Alton to Memphis) 9 St. Louis,
MO
Memphis,TN Steamboat Deluxe See prices
Home For the Holidays 2021 (New Orleans to Memphis) 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
Cajun Creole Culinary Experience 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Creole Christmas 2021 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Heartland Heritage 2021 9 Minneapolis,
MN
Red Wing,
MN
Steamboat Deluxe See prices
Bridge Cruise 2021 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
American Culinary Experience 2021 (Louisville to Alton) 9 Louisville,
KY
Alton,
IL
Steamboat Deluxe See prices
Thanksgiving 2021 (New Orleans Roundtrip) 9 New Orleans,
LA
New Orleans,
LA
Steamboat Deluxe See prices
New Year's Celebration 2021 9 New Orleans,
LA
New Orleans,
LA
Steamboat Deluxe See prices
Star-Spangled Cruise 2021 (Louisville to Pittsburgh) 9 Louisville,
KY
Pittsburgh,
PA
Steamboat Deluxe See prices
Thanksgiving 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Music of the 50s and 60s 2021 9 Louisville,
KY
Memphis,TN Steamboat Deluxe See prices
Bourbon 2021 (Memphis to Louisville) 9 Memphis,TN Louisville,
KY
Steamboat Deluxe See prices
Lincoln's Illinois 2021 (Ottawa to Alton) 9 Chicago,
IL
Alton,
IL
Steamboat Deluxe See prices
Civil War 2021 (Chattanooga to Memphis) 9 Chattanooga,
TN
Memphis,TN Steamboat Deluxe See prices
Lincoln's Illinois 2021 (Memphis to Ottawa) 9 Memphis,TN Ottawa,
IL
Steamboat Deluxe See prices
Ohio River Exploration 2021 (Pittsburgh to Louisville) 9 Pittsburgh,
PA
Louisville,
KY
Steamboat Deluxe See prices
Founder's Cruise 2021 (Louisville to Alton) 9 Louisville,
KY
Alton,
IL
Steamboat Deluxe See prices
Autumn on the River 2021 (Memphis to Chattanooga) 9 Memphis,TN Chattanooga,
TN
Steamboat Deluxe See prices
American Culinary Experience 2021 (Memphis to Alton) 9 Memphis,TN Alton,
IL
Steamboat Deluxe See prices
Salute to Veterans 2021 9 New Orleans,
LA
Memphis,TN Steamboat Deluxe See prices
Star-Spangled Cruise 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Mark Twain's Mississippi 2021 9 St. Louis,
MO
Red Wing,
MN
Steamboat Deluxe See prices
Autumn on the River 2021 (Chattanooga to Memphis) 9 Chattanooga,
TN
Memphis,TN Steamboat Deluxe See prices
Civil War 2021 (Memphis to Chattanooga) 9 Memphis,TN Chattanooga,
TN
Steamboat Deluxe See prices
Autumn on the River 2021 (Red Wing to St. Louis) 9 Minneapolis,
MN
St. Louis,
MO
Steamboat Deluxe See prices
Civil War 2021 (Memphis to New Orleans) 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Breast Cancer Awareness Cruise 2021 9 St. Louis,
MO
New Orleans,
LA
Steamboat Deluxe See prices
American River Golf Classic 2021 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Past Guest Reunion Cruise 2021 9 Memphis,TN New Orleans,
LA
Steamboat Deluxe See prices
Big Band 2021 (Memphis to Louisville) 9 Memphis,TN Louisville,
KY
Steamboat Deluxe See prices
Kentucky Derby Cruise 2021 9 Cincinnati,
OH
Louisville,
KY
Steamboat Deluxe See prices
Founder's Cruise 2021 (Louisville to St. Louis) 9 Louisville,
KY
St. Louis,
MO
Steamboat Deluxe See prices
American Culinary Experience 2021 (Alton to Memphis) 9 St. Louis,
MO
Memphis,TN Steamboat Deluxe See prices
Mississippi River Gateway Cruise (New Orleans to St. Louis) 11 New Orleans,
LA
St. Louis,
MO
ACL Deluxe See prices
Grand Heartland Cruise 15 St. Paul,
MN
New Orleans,
LA
ACL Deluxe See prices
America's Great River 2022 (St. Paul to New Orleans) 15 St. Paul,
MN
New Orleans,
LA
Viking Deluxe See prices
America's Great River 2022 (New Orleans to St. Paul) 15 New Orleans,
LA
St. Paul,
MN
Viking Deluxe See prices
America's Great River 2023 (St. Paul to New Orleans) 15 St. Paul,
MN
New Orleans,
LA
Viking Deluxe See prices
America's Great River 2023 (New Orleans to St. Paul) 15 New Orleans,
LA
St. Paul,
MN
Viking Deluxe See prices
The Mighty Mississippi 2021 16 Minneapolis,
MN
New Orleans,
LA
Steamboat Deluxe See prices
Complete Mississippi River Cruise 2021 22 New Orleans,
LA
St. Paul,
MN
ACL Deluxe See prices